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Scleritis can be classified as anterior scleritis and posterior scleritis. Anterior scleritis is the most common variety, accounting for about 98% of the cases. It is of two types : Non-necrotising and necrotising. Non-necrotising scleritis is the most common, and is further classified into diffuse and nodular type based on morphology.
In women, it includes structures such as ovaries, fallopian tubes, a uterus, and a vagina, while in men, it includes testes, vas deferens, seminal vesicles, prostate, and the penis. Autoimmune diseases of the reproductive system can affect both male and female fertility and reproductive health.
Episcleritis of a 40 year old female. Symptoms of episcleritis typically include painless redness of the eye (mild pain is possible but atypical), and watery eyes. [2] The pain of episcleritis is typically mild, less severe than in scleritis, [3] and may be tender to palpation.
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About 3.0 to 7.5% of people with ulcerative colitis have PSC, and 80% of people with PSC have some form of IBD. [3] Diagnosis usually occurs in people in their 30s or 40s. [3] Individuals of Northern European ancestry are affected more often than people of Southern European or Asian descent. [2] Men are affected more often than women. [7]
[3] [6] [4] [8] [9] The most common forms of ocular involvement are usually mild and often consist of unilateral or bilateral episcleritis and/or scleritis, that is often anterior and could be lingering or relapsing. [3] [4] Scleritis that is necrotizing is found to be exceedingly rare. [3] Less often, conjunctivitis occurs.
The diagnosis is based on involvement of less than 10% of the skin. [2] It is known as TEN when more than 30% of the skin is involved and an intermediate form with 10 to 30% involvement. [3] A positive Nikolsky's sign is helpful in the diagnosis of SJS and TEN. [9] A skin biopsy is helpful, but not required, to establish a diagnosis of SJS and ...
Small aneurysms are strung like the beads of a rosary, [4] therefore making this "rosary sign" an important diagnostic feature of the vasculitis. [5] PAN is sometimes associated with infection by the hepatitis B or hepatitis C virus. [6] The condition may be present in infants. [7] PAN is a rare disease. [6]