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Low energy levels and stress: The AMP-dependent protein kinase AMPK phosphorylates and thereby activates TSC1-TSC2 by phosphorylating at least 2 residues of TSC2. [7] Hypoxia: The Hypoxia-inducible factor α HIFα induces REDD1 at low oxygen levels. REDD1 has been shown to activate TSC1-TSC2 by neutralisation of AKT dependent inhibition. [8]
The 21st TSC originated as a maintenance support headquarters under Seventh Army Support Command, the brigade's first home was Taylor Barracks, Mannheim, Germany. After the United States military withdrawal from France in 1967 and the organization of the U.S. Theater Army Support Command, Europe, informally known as TASCOM, the brigade became ...
Designed as a heavy prime mover for tank transporting, the hard-cab Diamond T 980 [2] was the product of the Diamond T Company in Chicago.In 1940 the British Purchasing Commission, looking to equip the British Army with a vehicle capable of transporting larger and heavier tanks, approached a number of American truck manufacturers to assess their models.
The prime symbol ′ is also sometimes used informally to denote minutes. [3] In the UTC time standard , a minute on rare occasions has 61 seconds, a consequence of leap seconds ; there is also a provision to insert a negative leap second, which would result in a 59-second minute, but this has never happened in more than 40 years under this system.