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A bone scan or bone scintigraphy / s ɪ n ˈ t ɪ ɡ r ə f i / is a nuclear medicine imaging technique used to help diagnose and assess different bone diseases. These include cancer of the bone or metastasis, location of bone inflammation and fractures (that may not be visible in traditional X-ray images), and bone infection (osteomyelitis). [1]
A skeletal survey (also called a bone survey [1]) is a series of X-rays of all the bones in the body, or at least the axial skeleton and the large cortical bones. A very common use is the diagnosis of multiple myeloma , where tumour deposits appear as "punched-out" lesions.
In case of continued stress, a fracture line through the thickened cortex and a region of sclerosis may be observed. MRI is of great value for early diagnosis and displaying bone marrow edema, while scintigraphy is useful for showing increased metabolic activity within the bone. However, MRI is preferred since scintigraphy lacks specificity.
SPECT can be used to complement any gamma imaging study, where a true 3D representation can be helpful, such as tumor imaging, infection imaging, thyroid imaging or bone scintigraphy. Because SPECT permits accurate localisation in 3D space, it can be used to provide information about localised function in internal organs, such as functional ...
DXA BMD results adjusted in this manner are referred to as the bone mineral apparent density (BMAD) and are a ratio of the bone mineral content versus a cuboidal estimation of the volume of bone. Like the results for aBMD, BMAD results do not accurately represent true bone mineral density, since they use approximations of the bone's volume.
Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).
The muscles of the hand can be subdivided into two groups: the extrinsic and intrinsic muscle groups. The extrinsic muscle groups are the long flexors and extensors. They are called extrinsic because the muscle belly is located on the forearm. The intrinsic group are the smaller muscles located within the hand itself. The muscles of the hand ...
In order to obtain spatial information about the gamma-ray emissions from an imaging subject (e.g. a person's heart muscle cells which have absorbed an intravenous injected radioactive, usually thallium-201 or technetium-99m, medicinal imaging agent) a method of correlating the detected photons with their point of origin is required.