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Myosin X is an unconventional myosin motor, which is functional as a dimer. The dimerization of myosin X is thought to be antiparallel. [53] This behavior has not been observed in other myosins. In mammalian cells, the motor is found to localize to filopodia. Myosin X walks towards the barbed ends of filaments.
Myo10 is a member of an evolutionarily ancient group of myosins whose tails contain MyTH4-FERM domains and that have been shown to have important functions in cellular protrusions based on actin bundles such as filopodia, microvilli, and inner ear stereocilia.
Myosin-9 also known as myosin, heavy chain 9, non-muscle or non-muscle myosin heavy chain IIa (NMMHC-IIA) is a protein which in humans is encoded by the MYH9 gene. [5] [6]Non-muscle myosin IIA (NM IIA) is expressed in most cells and tissues where it participates in a variety of processes requiring contractile force, such as cytokinesis, cell migration, polarization and adhesion, maintenance of ...
A non-contractile function is seen in specialized smooth muscle within the afferent arteriole of the juxtaglomerular apparatus, which secretes renin in response to osmotic and pressure changes, and also it is believed to secrete ATP in tubuloglomerular regulation of glomerular filtration rate.
Myosin-1, also known as 'striated muscle myosin heavy chain 1', is a protein that in humans is encoded by the MYH1 gene. [5] [6] This gene is most highly expressed in fast type IIX/D muscle fibres of vertebrates and encodes a protein found uniquely in striated muscle; it is a class II myosin with a long coiled coil tail that dimerizes and should not be confused with 'Myosin 1' encoded by the ...
17883 Ensembl ENSG00000109063 ENSMUSG00000020908 UniProt P11055 P13541 RefSeq (mRNA) NM_002470 NM_001099635 RefSeq (protein) NP_002461 NP_001093105 Location (UCSC) Chr 17: 10.63 – 10.66 Mb Chr 11: 66.97 – 66.99 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Myosin-3 is a protein that in humans is encoded by the MYH3 gene. Function Myosin is a major contractile protein which ...
544791 Ensembl ENSG00000006788 ENSMUSG00000060180 UniProt Q9UKX3 n/a RefSeq (mRNA) NM_003802 NM_001081250 RefSeq (protein) NP_003793 n/a Location (UCSC) Chr 17: 10.3 – 10.37 Mb Chr 11: 67.21 – 67.26 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Myosin-13 also known as myosin, heavy chain 13 is a protein which in humans is encoded by the MYH13 gene. Function MYH13 is a myosin ...
Myosin-10 also known as myosin heavy chain 10 or non-muscle myosin IIB (NM-IIB) is a protein that in humans is encoded by the MYH10 gene. [5] [6] Non-muscle myosins are expressed in a wide variety of tissues, but NM-IIB is the only non-muscle myosin II isoform expressed in cardiac muscle, where it localizes to adherens junctions within intercalated discs.