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PennyMac is a member of the Russell 2000 Index. [9] At the time of its IPO, PennyMac had more than 600 employees at its Moorpark, California headquarters, making it one of the largest private employers and biggest tenants in the city. [10] It moved to its current headquarters in Westlake Village in 2015. [11]
Impedance–pH monitoring is a technique used in the diagnosis of gastroesophageal reflux disease (GERD), by monitoring both impedance and pH. [ 1 ] [ 2 ] Patients with ongoing symptoms while on proton-pump inhibitor (PPI) therapy are commonly diagnosed with impedance–pH monitoring while continuing their medications.
Esophageal pH monitoring is performed for 24 or 48 hours and at the end of recording, a patient's tracing is analyzed and the results are expressed using six standard components. Of these 6 parameters, a pH score called Composite pH Score or DeMeester Score has been calculated, which is a global measure of esophageal acid exposure. A Demeester ...
The concept of pH was defined in 1909 by S. P. L. Sørensen, and electrodes were used for pH measurement in the 1920s. [24] In October 1934, Arnold Orville Beckman registered the first patent for a complete chemical instrument for the measurement of pH, U.S. Patent No. 2,058,761, for his "acidimeter", later renamed the pH meter.
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Practical impedance-matching devices will generally provide best results over a specified frequency band. The concept of impedance matching is widespread in electrical engineering, but is relevant in other applications in which a form of energy, not necessarily electrical, is transferred between a source and a load, such as in acoustics or optics.
High-resolution manometry (HRM) is a gastrointestinal motility diagnostic system that measures intraluminal pressure activity in the gastrointestinal tract using a series of closely spaced pressure sensors. For a manometry system to be classified as "high-resolution" as opposed to "conventional", the pressure sensors need to be spaced at most 1 ...