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Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...
Dupilumab blocks IL-4 receptors, inhibiting subsequent inflammatory activities of IL-4 and IL-13. [ 29 ] Tezepelumab binds to thymic stromal lymphopoietin (TSLP), which is an inflammatory cytokine in the airway epithelial cells involved in asthma exacerbations, inhibiting subsequent inflammatory responses.
When associated with significant airflow limitation, emphysema is a major subtype of chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized by long-term breathing problems and poor airflow. [10] [11] Without COPD, the finding of emphysema on a CT lung scan still confers a higher mortality risk in tobacco smokers ...
An inhaler (puffer, asthma pump or allergy spray) is a medical device used for delivering medicines into the lungs through the work of a person's breathing. This allows medicines to be delivered to and absorbed in the lungs, which provides the ability for targeted medical treatment to this specific region of the body, as well as a reduction in the side effects of oral medications.
However, asthma is rarely the only symptom, and not all people with food or other allergies have asthma [17] Sulfite sensitivity Asthma can occur in reaction to ingestion or inhalation of sulfites, which are added to foods and wine as preservatives. [18] Salicylate sensitivity Salicylates can trigger asthma in sensitive individuals. Salicylates ...
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When chronic bronchitis occurs together with decreased airflow it is known as chronic obstructive pulmonary disease (COPD). [27] [26] Many people with chronic bronchitis have COPD; however, most people with COPD do not also have chronic bronchitis. [10] [28] Estimates of the number of people with COPD who have chronic bronchitis are 7–40%.
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