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Some have suggested this is where blood lactate reaches a concentration of 2 mmol/litre (at rest it is around 1). [3] The anaerobic energy system increases the ability to produce blood lactate during maximal exercise, resulting from an increased amount of glycogen stores [clarification needed] and glycolytic enzymes. [2]
Here you can see a typical test where the first lactate threshold is at around 210-215 power output and their second lactate threshold is at 260-265.
The result can be detected with high levels of lactate and low levels of bicarbonate. This is usually considered the result of illness but also results from strenuous exercise. The effect on pH is moderated by the presence of respiratory compensation. Lactic acidosis is usually the result of tissue hypoxia which is not the same as arterial hypoxia.
Cori cycle. The Cori cycle (also known as the lactic acid cycle), named after its discoverers, Carl Ferdinand Cori and Gerty Cori, [1] is a metabolic pathway in which lactate, produced by anaerobic glycolysis in muscles, is transported to the liver and converted to glucose, which then returns to the muscles and is cyclically metabolized back to lactate.
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The by-product of anaerobic glycolysis—lactate—has traditionally been thought to be detrimental to muscle function. [13] However, this appears likely only when lactate levels are very high. Elevated lactate levels are only one of many changes that occur within and around muscle cells during intense exercise that can lead to fatigue.
VT1 is thought to reflect a person's anaerobic threshold — the point at which the oxygen supplied to the muscles no longer meets its oxygen requirements at a given work rate — and therefore lactate threshold — the point at which lactate begins to accumulate in the blood, because with ongoing dependence on anaerobic glycolysis, increasing ...
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