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Among surviving patients with available data, both TAVR and surgery led to improvements in health status at 5 years (NYHA functional class I or II, 89.0% and 92.7%, respectively; average...
Bottom line. Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure that involves replacing the aortic valve in people with aortic stenosis. It has several benefits...
Most TAVR procedures were performed through the common femoral artery (91.8%), and most study participants (60.6%) were treated with balloon-expandable valve . The in-hospital mortality rate for the study population was 4.4% and the observed success rate was 91.3%.
TAVR is minimally invasive, which means it uses smaller incisions than open-heart valve surgery. It may be an option for people who can't have heart surgery to replace the aortic valve. TAVR can help reduce chest pain, shortness of breath and other symptoms of aortic valve stenosis.
QuestionWhy have mortality rates after transcatheter aortic valve replacement (TAVR) plateaued since 2019, despite modest declines in patient-level risk and procedural improvements over the same time period?
The 2021 ESC/EACTS guidelines for the management of valvular heart disease recommended TAVR in older patients ≥75 years or in those who are high risk. The aim of this study was to determine the survival and the factors predicting mortality after TAVR in according to age. Methods.
TAVR has now been done in thousands of patients in the US and Europe with a procedural success rate of 90%. The 30 day mortality rates have varied from 3-15%. At 2 years, some studies have shown mortality rates of about 35%.
The difference in KM rates for the primary endpoint of all-cause mortality or disabling stroke for TAVR and surgery remained broadly consistent over time: −1.8% at year 1; −2.0% at year 2; and −2.9% at year 3 (Central Illustration).
The transcatheter aortic valve replacement procedure has a 90% success rate. Early on, clinical studies and trials found that TAVR was more likely to be successful and less likely to cause death or major complications among people with higher risks for complications from surgery.
Transcatheter aortic valve replacement (TAVR) becomes the leading therapeutic choice for severe aortic stenosis. There is a growing body of knowledge on long-term survival out-comes, but available data from real-world observational studies are scarce.