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Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Pain and sensory abnormalities can persist for months or years after treatment completion. Some patients may experience “coasting,” where symptoms intensify after completion of treatment. [3] As such, patients can be cancer-free and still suffer from disabling neuropathy induced by cancer treatment. [3]
Symptomatic features of paraneoplastic syndrome cultivate in four ways: endocrine, neurological, mucocutaneous, and hematological.The most common presentation is a fever (release of endogenous pyrogens often related to lymphokines or tissue pyrogens), but the overall picture will often include several clinical cases observed which may specifically simulate more common benign conditions.
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [3] [4] Cancer can be difficult to diagnose because its signs and symptoms are often nonspecific, meaning they may be general phenomena that do not point directly to a specific disease process.
Aphasia can be caused by a head injury or stroke, and the onset will usually be sudden, or it can be caused by a disease such as frontotemporal dementia, in which case the communication ...
Since there is no definitive diagnostic test, other conditions have to be ruled out before this rare condition can be diagnosed. The main differential diagnosis is polymyalgia rheumatica (PMR), although pain, stiffness and weakness at the level of the shoulders and pelvic girdle with associated systemic symptoms ( fever , malaise , fatigue ...
Molly Smith experienced pins and needles in her hands and feet, which eventually led to the discovery of a cyst and a diagnosis of ovarian cancer. As a summer camp volunteer in 2022, Molly Smith ...
Williams, who also has Graves' disease and lymphedema, was diagnosed in 2023 after she “began to lose words, act erratically at times and have difficulty understanding financial transactions ...