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Klinefelter syndrome (KS), also known as 47,XXY, is a chromosome anomaly where a male has an extra X chromosome. [10] These complications commonly include infertility and small, poorly functioning testicles (if present).
45,X/46,XY mosaicism, also known as X0/XY mosaicism and mixed gonadal dysgenesis, [1] is a mutation of sex development in humans associated with sex chromosome aneuploidy and mosaicism of the Y chromosome.
Microorchidism is a genetic disorder found in males, characterized by abnormally small testes; it is the opposite of macroorchidism, which is characterized by abnormally large testes.
Born March 20, 1912, in Baltimore, Klinefelter studied first at the University of Virginia, Charlottesville, and then attained his medical degree from Johns Hopkins School of Medicine. [1]
Klinefelter is a German surname, which is a variant of Kleinfelder. [1] This is a topographic name for a person who worked a smallholding, or a toponymic surname for a person from one of the places called Kleinfeld in Germany. [2]
Kleinfelder, Inc. is an engineering, construction management, design and environmental professional services firm. Kleinfelder operates over 100 office locations in the United States, Canada, and Australia. [2]
Sexual anomalies, also known as sexual abnormalities, are a set of clinical conditions due to chromosomal, gonadal and/or genitalia variation.Individuals with congenital (inborn) discrepancy between sex chromosome, gonadal, and their internal and external genitalia are categorised as individuals with a disorder of sex development (DSD). [1]
The coloration of tortoiseshell and calico cats is a visible manifestation of X-inactivation. The black and orange alleles of a fur coloration gene reside on the X chromosome.
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