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N-Acetylanthranilic acid can be synthesized from 2-bromoacetanilide via palladium-catalyzed carbonylation in tri-n-butylamine-water at 110–130 °C, under 3 atm of carbon monoxide. [4] In the laboratory, it can be easily synthesized from anthranilic acid and acetic anhydride. N-Acetylanthranilic acid exhibits triboluminescence when crushed. [5]
Fenamic acid is a derivative of anthranilic acid, [18]: 235 which in turn is a nitrogen isostere of salicylic acid, which is the active metabolite of aspirin. [ 18 ] : 235 Several non-steroidal anti-inflammatory drugs , including mefenamic acid , tolfenamic acid , flufenamic acid , and meclofenamic acid are derived from fenamic acid or ...
Chemically, they are esters of anthranilic acid. While the United States Food and Drug Administration (FDA) has approved some of these compounds for use as food additives, [ citation needed ] cinnamyl anthranilate is banned by the FDA. [ 1 ]
Methyl anthranilate, also known as MA, methyl 2-aminobenzoate, or carbomethoxyaniline, is an ester of anthranilic acid. Its chemical formula is C 8 H 9 NO 2 . It has a strong and fruity grape smell, and one of its key uses is as a flavoring agent.
phenylacetic acid, phenylacetone, amphetamine: Ephedrine, its salts, optical isomers, and salts of optical isomers methamphetamine: Ergonovine and its salts lysergic acid diethylamide: Ergotamine and its salts lysergic acid diethylamide: N-Acetylanthranilic acid, its esters, and its salts methaqualone
Ethyl butylacetylaminopropionate is an insect repellent whose trade name is IR3535 and was developed and commercialized by Merck KGaA (Germany). It is a colorless and odorless oil with a good skin feel in final products, and it is biodegradable.
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Folpet, a phthalimide, is a commercial fungicide. [3]Phthalimide is used as a precursor to anthranilic acid, a precursor to azo dyes and saccharin. [2]Alkyl phthalimides are useful precursors to amines in chemical synthesis, especially in peptide synthesis where they are used "to block both hydrogens and avoid racemization of the substrates". [4]