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Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant and eugeroic (wakefulness promoter) medication used primarily to treat narcolepsy, [3] [8] [15] a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. [16]
Double-blind randomized controlled trials have demonstrated the efficacy and tolerability of modafinil in pediatric ADHD. [102] [103] There are risks of serious side effects such as skin reactions, however these are rare and modafinil is not recommended for use in children.
A Cephalon-founded study in which patients were administered modafinil, methylphenidate, and a placebo found that modafinil produces "psychoactive and euphoric effects and feelings consistent with [methylphenidate]." [12] Like modafinil, armodafinil is an inhibitor and/or inducer of certain cytochrome P450 enzymes.
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Treatment of excessive daytime sleepiness (EDS) relies on identifying and treating the underlying disorder which may cure the person from the EDS. Drugs like modafinil, [22] armodafinil, [23] pitolisant [24] (Wakix), sodium oxybate (Xyrem) oral solution, have been
It is generally not recommended to take modafinil after noon; modafinil is a relatively long-acting drug with a half-life of 15 hours, and taking it during the later part of the day can make it harder to fall asleep at bedtime. [51] Vitamin B 12 was, in the 1990s, suggested as a remedy for DSPD, and is still recommended by some sources. Several ...
The wakefulness-promoting agent modafinil and its analogues (e.g., adrafinil, armodafinil) have been approved to treat narcolepsy and shift work sleep disorder. [6] These act as weak DRIs, [7] but this effect does not correlate with wakefulness-promoting effects, suggesting the effect is too weak to be of clinical significance.
Flmodafinil (developmental code names CRL-40,940, NLS-4, JBG01-41), also known as bisfluoromodafinil and lauflumide, is a wakefulness-promoting agent related to modafinil which has been developed for treatment of a variety of different medical conditions.
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related to: how much modafinil is too- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
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