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Phenylpropanolamine (PPA), sold under many brand names, is a sympathomimetic agent used as a decongestant and appetite suppressant. [9] [1] [10] [11] It was once common in prescription and over-the-counter cough and cold preparations.
Bucinnazine (AP-237, 1-butyryl-4-cinnamylpiperazine) is an opioid analgesic drug that was widely used in China to treat pain in cancer patients as of 1986. [1] It is one of the most potent compounds among a series of piperazine- amides first synthesized and reported in Japan in the 1970s.
Flunarizine is a selective calcium antagonist with moderate other actions including antihistamine, serotonin receptor blocking and dopamine D 2 blocking activity. Compared to other calcium channel blockers such as dihydropyridine derivatives, verapamil and diltiazem, flunarizine has low affinity to voltage-dependent calcium channels.
[3] [12] It has strong anabolic effects and weak androgenic effects, which give it a mild side effect profile and make it especially suitable for use in women and children. [3] [12] [13] NPP is a nandrolone ester and a long-lasting prodrug of nandrolone in the body. [3] NPP was first described in 1957 and was introduced for medical use in 1959. [3]
Cinnarizine is an antihistamine and calcium channel blocker of the diphenylmethylpiperazine group. [5] It is prescribed for nausea and vomiting due to motion sickness [6] or other sources such as chemotherapy, [7] vertigo, [8] or Ménière's disease. [9]
AP-238 is an opioid designer drug related to drugs such as azaprocin and bucinnazine, with around the same potency as morphine. [2] It was first discovered in Italy in the 1960s but was never marketed, [3] subsequently appearing on the illicit market around 2020 and being detected in both Slovenia and the USA.
Over the last 25 years, (ED) medications such as Viagra and others have become common and normal pieces of bedroom tool kit. These little pills have helped hundreds of millions of men all over the ...
The phenylpropanoids are a diverse family of organic compounds that are biosynthesized by plants from the amino acids phenylalanine and tyrosine in the shikimic acid pathway. [1] Their name is derived from the six-carbon, aromatic phenyl group and the three-carbon propene tail of coumaric acid , which is the central intermediate in ...