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Osteoporosis can affect nearly 1 in 3 women and the bone loss is the most rapid within the first 2–3 years after menopause. This can be prevented by menopause hormone therapy or MHT, which is meant to prevent bone loss and the degradation of the bone microarchitecture and is noted to reduce the risk of fractures in bones by 20-30%.
Estrogen and other hormones are given to postmenopausal women in order to prevent osteoporosis as well as treat the symptoms of menopause such as hot flashes, vaginal dryness, urinary stress incontinence, chilly sensations, dizziness, fatigue, irritability, and sweating. Fractures of the spine, wrist, and hips decrease by 50 to 70% and spinal ...
Estradiol is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor, the biological target of estrogens like endogenous estradiol. [11] Due to its estrogenic activity, estradiol has antigonadotropic effects and can inhibit fertility and suppress sex hormone production in both women and men.
A decrease in estrogen levels can lead to osteoporosis, cognitive disorders, and can affect many important genes related to normal physiological function. [ citation needed ] Estrogen can be divided into four classes: 1) Animal Estrogens that includes estrone (E1), estradiol (E2), and estriol (E3); 2) Plant Estrogens ( Phytoestrogens ); 3 ...
Hypoestrogenism, or estrogen deficiency, refers to a lower than normal level of estrogen. It is an umbrella term used to describe estrogen deficiency in various conditions. Estrogen deficiency is also associated with an increased risk of cardiovascular disease, [1] and has been linked to diseases like urinary tract infections [2] and osteoporosis.
A young woman revealed she was diagnosed with osteoporosis after using Ozempic for a year.. The 30-year-old, named Avery, shared that she began using the medication without a prescription from her ...
The results suggest that bone loss could be an effect of levothyroxine use in older adults, even when used at the appropriate dosage, which could be a concern in terms of osteoporosis risk. Is ...
Estradiol affects target tissues mainly by interacting with two nuclear receptors called estrogen receptor α (ERα) and estrogen receptor β (ERβ). [ 36 ] [ 37 ] One of the functions of these estrogen receptors is the modulation of gene expression .