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One of Pavlov’s dogs with a saliva-catch container and tube surgically implanted in its muzzle, Pavlov Museum, 2005. The history of animal testing goes back to the writings of the Ancient Greeks in the 4th and 3rd centuries BCE, with Aristotle (384–322 BCE) and Erasistratus (304–258 BCE) one of the first documented to perform experiments on nonhuman animals. [1]
Animal testing, also known as animal experimentation, animal research, and in vivo testing, is the use of non-human animals, such as model organisms, in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in ...
The history of zoology before Charles Darwin's 1859 theory of evolution traces the organized study of the animal kingdom from ancient to modern times. Although the concept of zoology as a single coherent field arose much later, systematic study of zoology is seen in the works of Aristotle and Galen in the ancient Greco-Roman world.
The De Virga world map was made by Albertinus de Virga between 1411 and 1415. Albertin de Virga, a Venetian, is also known for a 1409 map of the Mediterranean, also made in Venice. The world map is circular, drawn on a piece of parchment 69.6 cm × 44 cm (27.4 in × 17.3 in). It consists of the map itself, about 44 cm (17 in) in diameter, and ...
The first known footprints on land date to 530 Ma. [74] 520 Ma Earliest graptolites. [75] 511 Ma Earliest crustaceans. [76] 505 Ma Fossilization of the Burgess Shale: 500 Ma Jellyfish have existed since at least this time. 485 Ma First vertebrates with true bones (jawless fishes). 450 Ma First complete conodonts and echinoids appear. 440 Ma
British Parliament passed the first national animal protection legislation, and the first animal protection and vegetarian organizations formed in the U.S. and U.K. [13] The American and British anti-vivisection movements grew in the late 19th century, led by Frances Power Cobbe in Britain and culminating in the Brown Dog affair, then declining ...
Anaximander (Greek, 610 BC–545 BC) was a student of Thales of Miletus. He was taught that the first life was formed by spontaneous generation in the mud. Later animals came into being by transmutations, left the water, and reached dry land. Man was derived from lower animals, probably aquatic.
The first rodent behavioral study was carried out in 1822, a purely observational study [2], while quantitative rodent behavioral testing began in the late 19th century [1] [2]. Currently, rodents are commonly used in animal testing for physiological, pathological and behavioral scientific studies, particularly mice and rats , but also guinea ...
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