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Tetrahydrocannabinolic acid (THCA, 2-COOH-THC; conjugate base tetrahydrocannabinolate) is a precursor of tetrahydrocannabinol (THC), an active component of cannabis. [1]THCA is found in variable quantities in fresh, undried cannabis, but is progressively decarboxylated to THC with drying, and especially under intense heating such as when cannabis is smoked or cooked into cannabis edibles.
However, cannabis does not naturally contain significant amounts of THC. Instead, tetrahydrocannabinolic acid (THCA) is found naturally in raw and live cannabis and is non-intoxicating. Over time, THCA slowly converts to THC through a process of decarboxylation over the course of roughly a year, but can be sped up with exposure to high ...
Consequently, a high-fat meal increases levels of 11-hydroxy-THC by only 25% and most of the increase in bioavailability is due to increased levels of THC. [32] The bioavailability of THC when smoking or inhaling is approximately 25%, with a range of 2% to 56% (although most commonly between 10 and 35%).
Even though marijuana currently remains illegal in North Carolina, there are other cannabis-related products for sale in the state. Learn what they are. Marijuana vs. CBD vs. delta-8 vs. THC: What ...
Because the law limited only Δ 9-THC levels, many other cannabinoids are generally considered legal to sell and are widely available in stores and online, including Δ 8-THC, Δ 10-THC, HHC, and THCP, [68] [69] but have not had the same in-depth research that the Δ 9 isomer has on the human body; carrying potential risks in the short- or long ...
(Legal products that are marketed as delta-9 in Texas are hemp-derived cannabinoids with less than 0.3 percent THC.) The only difference between THCa and delta-9 is the location of a double bond ...
Cannabinoid ratios: On average, Cannabis indica has higher levels of THC compared to CBD, whereas Cannabis sativa has lower levels of THC to CBD. [6] However, huge variability exists within either species. A 2015 study shows the average THC content of the most popular herbal cannabis products in the Netherlands has decreased slightly since 2005 ...
Despite the CBD and THC having the same molecular weight, multiple analytical methods are able to differentiate them. [11] "on the recovery of both THC (86.7−90.0%) and CBD (92.3−95.6%). The slightly lower recovery of THC can be explained by the fact that THC is less polar than CBD and more likely to remain in the nonpolar sunflower oil." [11]