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There is a large number of methods for the determination of particle size, and it is important to acknowledge that these different methods are not expected to give identical results. The size of a particle depends on the method used for its measurement, and it is important to choose the method that is most relevant to the application.
In all methods the size is an indirect measure, obtained by a model that transforms, in abstract way, the real particle shape into a simple and standardized shape, like a sphere (the most usual) or a cuboid (when minimum bounding box is used), where the size parameter (ex. diameter of sphere) makes sense.
Microfluidic diffusional sizing (MDS) is a method to measure the size of particles based on the degree to which they diffuse within a microfluidic laminar flow. [1] It allows size measurements to be taken from extremely small quantities of material (nano-grams) and is particularly useful when sizing molecules which may vary in size depending on their environment - e.g. protein molecules which ...
The angle of diffraction increases as particle size decreases, so that this method is particularly good for measuring sizes between 0.1 and 3,000 μm. Advances in sophisticated data processing and automation have allowed this to become the dominant method used in industrial PSD determination.
Laser diffraction analysis, also known as laser diffraction spectroscopy, is a technology that utilizes diffraction patterns of a laser beam passed through any object ranging from nanometers to millimeters in size [1] to quickly measure geometrical dimensions of a particle. This particle size analysis process does not depend on volumetric flow ...
Imaging particle analysis is a technique for making particle measurements using digital imaging, one of the techniques defined by the broader term particle size analysis. The measurements that can be made include particle size , particle shape (morphology or shape analysis and grayscale or color , as well as distributions (graphs) of ...
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