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The osteoclast releases hydrogen ions through the action of carbonic anhydrase (H 2 O + CO 2 → HCO 3 − + H +) through the ruffled border into the resorptive cavity, acidifying and aiding dissolution of the mineralized bone matrix into Ca 2+, H 3 PO 4, H 2 CO 3, water and other substances. Dysfunction of the carbonic anhydrase has been ...
Osteoclasts break down bone tissue, and along with osteoblasts and osteocytes form the structural components of bone. In the hollow within bones are many other cell types of the bone marrow . Components that are essential for osteoblast bone formation include mesenchymal stem cells (osteoblast precursor) and blood vessels that supply oxygen and ...
Bone tissue is a dynamic system with active metabolism. [24] Bone tissue remodelling or bone remodeling is a successive chain of old bone matrix removal and its replacement with a new one. [25] These processes make a child’s skeleton grow and extend, while childhood is characterized by bone tissue growth rather than its resorption.
The canal of the nutrient foramen is directed away from more active end of bone when one end grows more than the other. When bone grows at same rate at both ends, the nutrient artery is perpendicular to the bone. Most other bones (e.g. vertebrae) also have primary ossification centers, and bone is laid down in a similar manner. Secondary centers
Water accelerates the process by leaching essential organic minerals from bone. As such, soil type plays a role, because it will affect the water content of the environment. For example, some soils, like clay soils, retain water better than others, like sandy or silty soils.
"Bones break because of either two main reasons. One, the force on the broken is stronger than the bone can take. Or two, the bone itself is weakened for some reason," said Dr. Claire Shannon, a ...
Modified (flattened) osteoblasts become the lining cells that form a protective layer on the bone surface. The mineralised matrix of bone tissue has an organic component of mainly collagen called ossein and an inorganic component of bone mineral made up of various salts. Bone tissue is mineralized tissue of two types, cortical bone and ...
Osteoid makes up about fifty percent of bone volume and forty percent of bone weight. It is composed of fibers and ground substance. The predominant type of fiber is type I collagen and comprises ninety percent of the osteoid. The ground substance is mostly made up of chondroitin sulfate and osteocalcin.