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Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by an abnormally large increase in heart rate upon sitting up or standing. [1] POTS is a disorder of the autonomic nervous system that can lead to a variety of symptoms, [10] including lightheadedness, brain fog, blurred vision, weakness, fatigue, headaches, heart palpitations, exercise intolerance, nausea ...
Investigations may be performed to identify underlying disease processes that may have led to the development of symptoms or autonomic neuropathy. Symptomatic treatment is available for many symptoms associated with dysautonomia, and some disease processes can be directly treated. Depending on the severity of the dysfunction, dysautonomia can ...
Anyone can develop POTS, but it’s more common in women between the ages of 15 to 50. It usually starts after pregnancy, major surgery, trauma, or a viral illness, per the NINDS.
Diabetic nephropathy, damage to the kidney due to increased glomerular pressure and hyperfiltration can lead to end-stage chronic kidney disease that may require renal dialysis. [27] In most parts of the world, diabetes mellitus is the leading cause of end-stage kidney disease (ESKD).
A recent study found that features of POTS, such as the change in heart rate or blood pressure when going from laying down to sitting up, can affect the performance of elite swimmers. Why Ledecky ...
As the disease progresses, neuronal dysfunction correlates closely with the development of blood vessel abnormalities, such as capillary basement membrane thickening and endothelial hyperplasia, which contribute to diminished oxygen tension and hypoxia. Neuronal ischemia is a well-established characteristic of diabetic neuropathy.
A remission may be considered a partial remission or a complete remission. Each disease, type of disorder , or clinical trial can have its own definition of a partial remission. For example, a partial remission for cancer may be defined as a 50% or greater reduction in the measurable parameters of tumor growth as may be found on physical ...
Most people with erythromelalgia never go into remission and the symptoms are ever present at some level, whilst others get worse, or the EM is eventually a symptom of another disease such as systemic scleroderma. [citation needed] Some suffering with EM are prescribed ketamine topical creams as a way of managing pain on a long-term basis. [42]