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Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [2] [3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood.
Prochymal is a stem cell therapy made by Osiris Therapeutics. It is the first stem cell therapy approved by Canada. It is also the first therapy approved by Canada for acute graft-vs-host disease (GvHD). [1] Also known as remestemcel-L, Prochymal was sold to Australia-based Mesoblast in 2013 [2] at which time its brand name was changed to Ryoncil.
The Stem Cell Network (SCN) is a Canadian non-profit that supports stem cell and regenerative medicine research, teaches the next generation of highly qualified personal, and delivers outreach activities across Canada. [1] [2] The Network has been supported by the Government of Canada, since inception in 2001.
This is a list of countries by stem cell research trials for the purpose of commercializing treatments as of June 2020, using data from ClinicalTrials.gov. [ 1 ] Rank
The term regenerative medicine is increasingly conflated with research on stem cell therapies. Some academic programs and departments retain the original broader definition while others use it to describe work on stem cell research. [23]
Bone marrow transplant is a form of stem cell therapy that has been used for many years because it has proven to be effective in clinical trials. [94] [95] Stem cell implantation may help in strengthening the left-ventricle of the heart, as well as retaining the heart tissue to patients who have suffered from heart attacks in the past. [96]
Mucolipidosis II (I-cell disease) Fucosidosis; Aspartylglucosaminuria; Alpha-mannosidosis; Other Wolman disease (acid lipase deficiency) Immunodeficiencies. T-cell deficiencies Ataxia-telangiectasia; DiGeorge syndrome; Combined T- and B-cell deficiencies Severe combined immunodeficiency (SCID), all types; Well-defined syndromes Wiskott ...
A regenerative medicine therapy is defined in section 506(g)(8) of the FD&C Act to include cell therapies, therapeutic tissue engineering, human cell and tissue products. Under the FDA's interpretation, gene therapies and genetically modified cells that have a lasting effect, such as CAR-T antitumor therapies, may also qualify as regenerative ...