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Asthma may also be classified as atopic (extrinsic) or non-atopic (intrinsic), based on whether symptoms are precipitated by allergens (atopic) or not (non-atopic). [12] While asthma is classified based on severity, at the moment there is no clear method for classifying different subgroups of asthma beyond this system. [102]
Early-onset atopic asthma is the most common phenotype of asthma in childhood, called intrinsic asthma in the earlier intrinsic/extrinsic classification. Patients with early-onset atopic asthma frequently have a family history of atopy, and are sensitised to common allergens. This phenotype usually responds well to inhaled corticosteroids, and ...
An exacerbation (attack) of asthma is experienced as a worsening of asthma symptoms with breathlessness and cough (often worse at night). In acute severe asthma, breathlessness may be so severe that it is impossible to speak more than a few words (inability to complete sentences). [5] [6]
Asthma is divided into two subgroups: atopic (extrinsic) and non-atopic (intrinsic). The atopic subgroup is closely associated with family history of the disease, whereas the non-atopic subgroup has its onset in adulthood and it is not caused by inheritance. It is known that non-atopic asthma has a more severe clinical course than atopic asthma.
Lung compliance is the difference of volume during inspiration and expiration. [ 7 ] Restrictive lung disease is characterized by reduced lung volumes, and therefore reduced lung compliance, either due to an intrinsic reason, for example a change in the lung parenchyma, or due to an extrinsic reason, for example diseases of the chest wall ...
GERD may be common in difficult-to-control asthma, but according to one study, treating it does not seem to affect the asthma. [33] When there is a clinical suspicion for GERD as the cause of the asthma, an Esophageal pH Monitoring is required to confirm the diagnosis and establish the relationship between GERD and asthma.
The terms "intrinsic incubation period" and "extrinsic incubation period" are used in vector-borne diseases. The intrinsic incubation period is the time taken by an organism to complete its development in the definitive host. The extrinsic incubation period is the time taken by an organism to develop in the intermediate host. [citation needed]
Asthma is considered an inflammatory-mediated disorder. On the right is an inflamed airway due to asthma. Colitis (inflammation of the colon) caused by Crohn's disease. Inflammatory abnormalities are a large group of disorders that underlie a vast variety of human diseases.
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