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Bicalutamide is used primarily in the treatment of early and advanced prostate cancer. [1] It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone analogue (GnRH analogue) or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), [2] [3] and as a monotherapy at a dosage of 150 mg/day ...
A 2015 Cochrane review found that NSAA monotherapy for prostate cancer had a greater risk of treatment discontinuation due to adverse effects than monotherapy with a GnRH agonist or surgical castration (RR = 1.82). [122] This included a greatly increased risk of breast pain (RR = 22.97) and gynecomastia (RR = 8.43). [122]
Prostate Cancer UK is now calling for NHS guidelines to “catch up to the modern evidence”. This disease is the most common cancer that affects men, with more than 52,000 diagnosed every year ...
The USPSTF has evaluated many interventions for prevention and found several have an expected net benefit in the general population. [10] Aspirin in men 45 to 79 and women 55 to 79 for cardiovascular disease; Colon cancer screening by colonoscopy, occult blood testing, or sigmoidoscopy in adults 45 to 75. [11]
If the cancer has spread beyond the prostate, treatment options change significantly, so most doctors who treat prostate cancer use a variety of nomograms to predict the probability of spread. Treatment by watchful waiting/active surveillance, HIFU, external-beam radiation therapy, brachytherapy, cryosurgery, and surgery are, in general ...
Its extract has been promoted as a prostate cancer medicine; however, according to the American Cancer Society, "available scientific studies do not support claims that saw palmetto can prevent or treat prostate cancer in humans". [100] Seasilver – an expensive dietary supplement made mostly from plant extracts and promoted by two U.S. companies.
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