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  2. Hereditary leiomyomatosis and renal cell cancer syndrome

    en.wikipedia.org/wiki/Hereditary_leiomyomatosis...

    It predisposes individuals to renal cell cancer, an association denominated hereditary leiomyomatosis and renal cell cancer. [1] [2] It is also associated with increased risk of uterine leiomyosarcoma. [3] The syndrome is caused by a mutation in the fumarate hydratase gene, which leads to an accumulation of fumarate.

  3. Leiomyosarcoma - Wikipedia

    en.wikipedia.org/wiki/Leiomyosarcoma

    A leiomyosarcoma (LMS) is a rare malignant (cancerous) smooth muscle tumor. [1] The word is from leio- 'smooth' myo- 'muscle' and sarcoma 'tumor of connective tissue'. The stomach, bladder, uterus, blood vessels, and intestines are examples of hollow organs made up of smooth muscles where LMS can be located; however, the uterus and abdomen are the most common sites.

  4. Hereditary cancer syndrome - Wikipedia

    en.wikipedia.org/wiki/Hereditary_cancer_syndrome

    A hereditary cancer syndrome (familial/family cancer syndrome, inherited cancer syndrome, cancer predisposition syndrome, cancer syndrome, etc.) is a genetic disorder in which inherited genetic mutations in one or more genes predispose the affected individuals to the development of cancer and may also cause early onset of these cancers.

  5. Carney triad - Wikipedia

    en.wikipedia.org/wiki/Carney_triad

    Carney triad (CT), named for J Aidan Carney, is considered to be a specific type of multiple endocrine neoplasia (MEN). The three classically associated tumors are a subset of gastric epithelioid leiomyosarcoma (it is now known that this subset is actually gastrointestinal stromal tumor arising from the interstitial cells of Cajal), pulmonary chondroma, and extra-adrenal paraganglioma.

  6. Uterine fibroid - Wikipedia

    en.wikipedia.org/wiki/Uterine_fibroid

    Leiomyosarcoma, pregnancy, ovarian cyst ... Genetic and hereditary causes are being considered and several epidemiologic findings indicate considerable genetic ...

  7. Uterine sarcoma - Wikipedia

    en.wikipedia.org/wiki/Uterine_sarcoma

    Uterine sarcoma is rare and mostly occurs in post-menopausal women. The most common type, leiomyosarcoma, is twice as common in Black women as it is in white women. Uterine sarcoma condition is most commonly treated by radical hysterectomy. If cancer has spread beyond the uterus, radiation, chemotherapy, and hormonal therapy may be used.

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  9. Causes of cancer - Wikipedia

    en.wikipedia.org/wiki/Causes_of_cancer

    Hereditary cancers are primarily caused by an inherited genetic defect. A cancer syndrome or family cancer syndrome is a genetic disorder in which inherited genetic mutations in one or more genes predisposes the affected individuals to the development of cancers and may also cause the early onset of these cancers. Although cancer syndromes ...

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