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A typical titration curve of a diprotic acid, oxalic acid, titrated with a strong base, sodium hydroxide.Both equivalence points are visible. Titrations are often recorded on graphs called titration curves, which generally contain the volume of the titrant as the independent variable and the pH of the solution as the dependent variable (because it changes depending on the composition of the ...
An acid–base titration is a method of quantitative analysis for determining the concentration of Brønsted-Lowry acid or base (titrate) by neutralizing it using a solution of known concentration (titrant). [1] A pH indicator is used to monitor the progress of the acid–base reaction and a titration curve can be constructed.
The word "titration" descends from the French word titrer (1543), meaning the proportion of gold or silver in coins or in works of gold or silver; i.e., a measure of fineness or purity. Tiltre became titre, [4] which thus came to mean the "fineness of alloyed gold", [5] and then the "concentration of a substance in a given sample". [6]
Gran plot. A Gran plot (also known as Gran titration or the Gran method) is a common means of standardizing a titrate or titrant by estimating the equivalence volume or end point in a strong acid -strong base titration or in a potentiometric titration. Such plots have been also used to calibrate glass electrodes, to estimate the carbonate ...
Karl Fischer titration. In analytical chemistry, Karl Fischer titration is a classic titration method that uses coulometric or volumetric titration to determine trace amounts of water in a sample. It was invented in 1935 by the German chemist Karl Fischer. [1][2] Today, the titration is done with an automated Karl Fischer titrator.
Winkler titration. The Winkler test is used to determine the concentration of dissolved oxygen in water samples. Dissolved oxygen (D.O.) is widely used in water quality studies and routine operation of water reclamation facilities to analyze its level of oxygen saturation. In the test, an excess of manganese (II) salt, iodide (I −) and ...
Titer (American English) or titre (British English) is a way of expressing concentration. [1] Titer testing employs serial dilution to obtain approximate quantitative information from an analytical procedure that inherently only evaluates as positive or negative. The titer corresponds to the highest dilution factor that still yields a positive ...
In chemical thermodynamics, isothermal titration calorimetry (ITC) is a physical technique used to determine the thermodynamic parameters of interactions in solution. [1][2] It is most often used to study the binding of small molecules (such as medicinal compounds) to larger macromolecules (proteins, DNA etc.) in a label-free environment. [3][4 ...