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  2. Pamrevlumab - Wikipedia

    en.wikipedia.org/wiki/Pamrevlumab

    Pamrevlumab (INN; [1] development code FG-3019) is a humanized monoclonal antibody designed for the treatment of idiopathic pulmonary fibrosis and pancreatic cancer. It binds to the connective tissue growth factor (CTGF) protein.

  3. Preclinical development - Wikipedia

    en.wikipedia.org/wiki/Preclinical_development

    In drug development, preclinical development (also termed preclinical studies or nonclinical studies) is a stage of research that begins before clinical trials (testing in humans) and during which important feasibility, iterative testing and drug safety data are collected, typically in laboratory animals.

  4. Largest-ever Ozempic and GLP-1 drug study finds they ... - AOL

    www.aol.com/finance/largest-ever-ozempic-glp-1...

    The study, led by researchers at the Veterans Affairs St. Louis Health Care System, found that use of these GLP-1s, as they are classified, was associated with reduced risks of a number of health ...

  5. Pieris Pharma Shares Pop On Preclinical Data From Potential ...

    www.aol.com/news/pieris-pharma-shares-pop...

    Pieris Pharmaceuticals Inc (NASDAQ: PIRS) announced the presentation of preclinical data for PRS-400, an inhaled Jagged-1 Anticalin protein for muco-obstructive lung diseases, at the European ...

  6. Lirilumab - Wikipedia

    en.wikipedia.org/wiki/Lirilumab

    Chemical and physical data; Formula: C 6452 H 9918 N 1698 O 2030 S 46: Molar mass: 145 228.93 g·mol −1: Lirilumab is a human monoclonal antibody designed for the ...

  7. Tactogen - Wikipedia

    en.wikipedia.org/wiki/TACTOGEN

    Tactogen is a public benefit corporation and start-up pharmaceutical company based in Palo Alto, California that is developing novel MDMA-like entactogens and psychedelics as medicines.

  8. Retifanlimab - Wikipedia

    en.wikipedia.org/wiki/Retifanlimab

    The US Food and Drug Administration (FDA) evaluated the safety and efficacy of retifanlimab based on PODIUM-201 (NCT03599713), an open-label, multiregional, single-arm study evaluating 65 participants with metastatic or recurrent locally advanced MCC who had not received prior systemic therapy for advanced disease.

  9. Xanomeline/trospium chloride - Wikipedia

    en.wikipedia.org/wiki/Xanomeline/trospium_chloride

    Preclinical data supports the hypothesis that xanomeline's central mechanism of action is mediated primarily through stimulation of brain muscarinic M 4 and M 1 receptors. [5] M 4 muscarinic receptors are most highly expressed in the midbrain, which controls motor and action planning, decision-making, motivation, reinforcement, and reward ...