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Chemical structure of methylprednisolone. Corticosteroids are used during acute multiple sclerosis relapses. Administration of high doses of intravenous corticosteroids, such as methylprednisolone, is the routine therapy for acute relapses.
IV infusion: Day 0 Etoposide: 40 mg/m 2: IV infusion over 1 hr: Days 1-4 Solu-Medrol - Methylprednisolone: 500 mg: IV bolus over 15 min: Days 1-5 High-dose Ara-C — cytarabine: 2000 mg/m 2: IV infusion over 2 hrs: Day 5 Platinol (cisplatin) 25 mg/m 2: IV continuous infusion over 24 hrs: Days 1-4
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares. Methylprednisolone and its derivatives can be administered ...
Methylprednisolone succinate, sold under the brand name Solu-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 succinate ester of methylprednisolone—which is used by intravenous administration.
Typical starting choices are hydrocortisone 100 mg IV q8h, prednisolone 30 mg IV q12h, or methylprednisolone 16–20 mg IV q8h. The last two are preferred due to less sodium retention and potassium wasting. 24-hour continuous infusion is preferred than the stated dosing.
Methylprednisolone acetate, sold under the brand names Depo-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 acetate ester of methylprednisolone—which is used in clinical and veterinary medicine.
Prednisolone is a corticosteroid, a steroid hormone used to treat certain types of allergies, inflammatory conditions, autoimmune disorders, and cancers, electrolyte imbalances and skin conditions.
Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF).
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