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Mees' lines can look similar to injury to the nail, which should not be confused with true Mees' lines. [1] Mees' lines appear after an episode of poisoning with arsenic, [2] thallium or other heavy metals or selenium, [3] opioid MT-45, and can also appear if the subject is suffering from kidney failure. [4] They have been observed in ...
Leukonychia striata, transverse leukonychia, or Mees' lines are a whitening or discoloration of the nail in bands or "stria" that run parallel to the lunula (nail base). This is commonly caused by physical injury or disruption of the nail matrix.
Muehrcke's lines were described by American physician Robert C. Muehrcke (1921–2003) in 1956. In a study published in BMJ, he examined patients with known chronic hypoalbuminemia and healthy volunteers, finding that the appearance of multiple transverse white lines was a highly specific marker for low serum albumin (no subject with the sign had SA over 2.2 g/dL), was associated with severity ...
Around 5% of those affected develop light-colored bands across the fingernail, called Mees' lines. [8] Chronic exposure eventually causes disease across multiple body systems, including peripheral neuropathy (numbness and tingling), enlargement of the liver and spleen , diabetes , heart disease , cognitive impairment , and damage to the portal ...
A new nail plate will form once the cause of the disease is removed. Onychomycosis, also known as tinea unguium, is a contagious infection of the nail caused by the same fungal organisms which cause ringworm of the skin (Trichophyton rubrum or T. mentagrophytes, rarely other trichophyton species or Epidermophyton floccosum [1]).
While Beau's lines are actual ridges and indentations in the nail plate, Muehrcke lines are areas of hypopigmentation without palpable ridges; they affect the underlying nail bed, and not the nail itself. Beau's lines should also be distinguished from Mees' lines of the fingernails, which are areas of discoloration in the nail plate.
The dark marks may look like 'raindrops' and these may be associated with Mees' lines across the nails. [6] The bumps typically appear 20 to 30 years after exposure to arsenic from usually a herbal medicine or contaminated water from wells. [6] AK may precede the development of squamous cell carcinoma or basal cell carcinoma. [7] [8]
Onychomadesis is defined by the nail plate's detachment from the matrix, its continuous connection to the nail bed, and, frequently but not always, shedding. [4] Beau lines are transverse ridges on the nail plates. [5]