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Extrapolating the fall in marathon world record times, Francois Peronnet of the University of Montreal predicted that the two-hour mark would be broken in 2028. [3] In 2017, The Economist reported that the average decrease in the marathon record was 8 seconds per year for the previous 50 years and 9.4 seconds per year for the previous 20 years.
N-Methylacetamide is a flammable, difficult to ignite, hygroscopic, crystalline, colourless solid with a faint odor that is soluble in water. [1] Several isomeric forms are known. [8] [9] In solution, it is 97–100% present as the Z isomer with a polymeric structure. [10] [4] The compound has a high dielectric constant of 191.3 at 32 °C. [11]
6-MeO-DMT, or 6-methoxy-N,N-dimethyltryptamine, also known as 6-OMe-DMT, is a serotonergic drug of the tryptamine family. [ 1 ] [ 2 ] It is the 6- methoxy derivative of the serotonergic psychedelic N , N -dimethyltryptamine (DMT) and is a positional isomer of the serotonergic psychedelic 5-MeO-DMT .
The chemical reactions of dimethylacetamide are typical of N,N-disubstituted amides. Hydrolysis of the acyl-N bond occurs in the presence of acids: CH 3 CON(CH 3) 2 + H 2 O + HCl → CH 3 COOH + (CH 3) 2 NH 2 + Cl −. However, it is resistant to bases. For this reason DMA is a useful solvent for reactions involving strong bases such as sodium ...
Methyl bromoacetate is an alkylating agent.It has been used to alkylate phenol and amino groups. [4] [5] Moreover, it can be used to make vitamins and pharmaceutical drugs.It is commonly used as a reagent in chemical modification of histidine. [2]
The full name of the chemical is 2,5-dimethoxy-4-bromoamphetamine. DOB has a stereocenter and R -(−)-DOB is the eutomer . This is an important finding as it is suggestive that it is targeting different receptors relative to most other phenethylamines (e.g. MDMA ) where the R -isomer serves as the distomer .
2-Bromo-4,5-methylenedioxyamphetamine (6-Bromo-MDA) is a lesser-known psychedelic drug and a substituted amphetamine. It was first synthesized by Alexander Shulgin. In his book PiHKAL, the dose is listed as 350 mg and the duration unknown. [1] It produces stimulant effects but with no psychedelic or empathogenic action. [1]
Methoxyphenamine was first synthesized at the Upjohn company by Woodruff and co-workers. [3] A later synthesis by Heinzelman, from the same company, corrects the melting point given for methoxyphenamine hydrochloride in the earlier paper, and describes an improved synthetic procedure, as well as resolution of the racemic methoxyphenamine.