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Myelin's best known function is to increase the rate at which information, encoded as electrical charges, passes along the axon's length. Myelin achieves this by eliciting saltatory conduction. [1] Saltatory conduction refers to the fact that electrical impulses 'jump' along the axon, over long myelin sheaths, from one node of Ranvier to the next.
Myelin basic protein (MBP) is a protein believed [weasel words] to be important in the process of myelination of nerves in the nervous system. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction . [ 5 ]
Myelin is formed by oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system.Therefore, the first stage of myelinogenesis is often defined as the differentiation of oligodendrocyte progenitor cells (OPCs) or Schwann cell progenitors into their mature counterparts, [4] followed by myelin formation around axons.
Nodes of Ranvier (/ ˈ r ɑː n v i eɪ / RAHN-vee-ay), [1] [2] also known as myelin-sheath gaps, occur along a myelinated axon where the axolemma is exposed to the extracellular space.
White matter is the tissue through which messages pass between different areas of grey matter within the central nervous system. The white matter is white because of the fatty substance (myelin) that surrounds the nerve fibers (axons). This myelin is found in almost all long nerve fibers, and acts as an electrical insulation.
Neurons are often grouped into a cluster known as a nucleus where they usually have roughly similar connections and functions. [3] Nuclei are connected to other nuclei by tracts of white matter . Glia are the supporting cells of the neurons and have many functions of which not all are clearly understood, but include providing support and ...
Soap Opera icon Leslie Charleson, who for decades played Monica Quartermaine on “General Hospital,” died Sunday morning after a long illness. She was 79. “It is with a heavy heart that I ...
The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the efficiency of axonal impulse conduction. [ 2 ] In humans, point mutations in PLP are the cause of Pelizaeus–Merzbacher disease (PMD), a neurologic disorder of myelin metabolism.