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A variety of other agents have been tried in bipolar disorder, including benzodiazepines, calcium channel blockers, L-methylfolate, and thyroid hormone. [2] Modafinil (Provigil) and pramipexole (Mirapex) have been suggested for treating cognitive dysfunction associated with bipolar depression, but evidence supporting their use is quite limited.
One meta-analysis of bipolar disorder in young people worldwide estimated that about 1.8% of people between the ages of seven and 21 have bipolar disorder. [127] Similar to adults, bipolar disorder in children and adolescents is thought to occur at a similar frequency in boys and girls. [127]
Bipolar I disorder requires confirmation of only 1 full manic episode for diagnosis, but may be associated with hypomanic and depressive episodes as well. [7] Diagnosis for bipolar II disorder does not include a full manic episode; instead, it requires the occurrence of both a hypomanic episode and a major depressive episode. [7]
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Cyclothymia (/ ˌ s aɪ k l ə ˈ θ aɪ m i ə /, siy-kluh-THIY-mee-uh), also known as cyclothymic disorder, psychothemia / psychothymia, [5] bipolar III, [6] affective personality disorder [7] and cyclothymic personality disorder, [8] is a mental and behavioural disorder [9] that involves numerous periods of symptoms of depression and periods of symptoms of elevated mood. [3]
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