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  2. Metformin (oral route) - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/metformin-oral-route/description/drg-20067074

    Under certain conditions, too much metformin can cause lactic acidosis. The symptoms of lactic acidosis are severe and quick to appear, and usually occur when other health problems not related to the medicine are present and are very severe, such as a heart attack or kidney failure. Symptoms of lactic acidosis include abdominal or stomach ...

  3. Metformin revisited - Mayo Clinic

    www.mayoclinic.org/medical-professionals/endocrinology/news/metformin...

    Slow-release metformin does not cause a rapid increase in the blood metformin levels, and a similar effect may occur when taking metformin during a meal. "Another concern about metformin is the potential for lactic acidosis.

  4. Diabetes: How do I help protect my liver? - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/diabetes/expert-answers/diabetes/FAQ...

    It's smart to think about how to protect your liver. Diabetes raises your risk of nonalcoholic fatty liver disease. In this condition, fat builds up in your liver even if you drink little or no alcohol. At least half of people living with type 2 diabetes have nonalcoholic fatty liver disease.

  5. Glipizide (oral route) - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/glipizide-oral-route/description/drg-20072046

    Kidney disease or; Liver disease—Higher blood levels of this medicine may occur, which may cause serious problems. Narrowed or blocked food passages (e.g., esophagus, stomach, or intestines), severe—Use with caution. The extended-release tablet may cause obstruction in patients with this condition.

  6. Diabetic nephropathy (kidney disease) - Symptoms and causes

    www.mayoclinic.org/diseases-conditions/diabetic-nephropathy/symptoms-causes/...

    Over time, diabetes that isn't well controlled can damage blood vessels in the kidneys that filter waste from the blood. This can lead to kidney damage and cause high blood pressure. High blood pressure can cause more kidney damage by raising the pressure in the filtering system of the kidneys.

  7. Statin side effects: Weigh the benefits and risks - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin...

    Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Rhabdomyolysis can cause extreme muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low.

  8. Mayo Clinic Study Reverses Current Thought on Treatment of...

    newsnetwork.mayoclinic.org/discussion/mayo-clinic-study-reverses-current...

    This condition is the consequence of damage done to the liver over many years. As cirrhosis progresses, more and more scar tissue forms, impeding proper liver functions. Metformin is used to treat high blood sugar levels caused by type 2 diabetes.

  9. Atenolol (oral route) - Mayo Clinic

    www.mayoclinic.org/drugs-supplements/atenolol-oral-route/description/drg-20071070

    Atenolol may cause heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort, dilated neck veins, extreme fatigue, irregular breathing or heartbeat, swelling of the face, fingers, feet, or lower legs, trouble breathing, or weight gain.

  10. My liver enzymes are elevated — Now what? - Mayo Clinic Press

    mcpress.mayoclinic.org/women-health/my-liver-enzymes-are-elevated-now-what

    What does it mean if my liver enzymes are elevated? Mild to moderate elevation in liver enzymes often means there is some type of inflammation within the liver. This matters because if the inflammation continues unabated for long enough, you could develop scarring in the liver, known as fibrosis.

  11. Liver problems - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/liver-problems/symptoms-causes/syc-20374502

    Anything that damages the liver also can cause liver problems, including viruses, alcohol use and obesity. Over time, conditions that damage the liver can lead to scarring, called cirrhosis. Cirrhosis can lead to liver failure, a life-threatening condition.