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In humans, hyperthermia is defined as a temperature greater than 37.5–38.3 °C (99.5–100.9 °F), depending on the reference used, that occurs without a change in the body's temperature set point. [3][10] The normal human body temperature can be as high as 37.7 °C (99.9 °F) in the late afternoon. [2] Hyperthermia requires an elevation from ...
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, [2] and is the cause of 60–70% of cases of dementia. [2][15] The most common early symptom is difficulty in remembering recent events. [1] As the disease advances, symptoms can include problems with language, disorientation (including ...
Sufficient stress from extreme external temperature may cause injury or death if it exceeds the ability of the body to thermoregulate. Hypothermia can set in when the core temperature drops to 35 °C (95 °F). [2] Hyperthermia can set in when the core body temperature rises above 37.5–38.3 °C (99.5–100.9 °F).
When the set point temperature returns to normal, a person feels hot, becomes flushed, and may begin to sweat. [3] Rarely a fever may trigger a febrile seizure, with this being more common in young children. [4] Fevers do not typically go higher than 41 to 42 °C (106 to 108 °F). [6]
Heat illness is a spectrum of disorders due to increased body temperature. It can be caused by either environmental conditions or by exertion. It includes minor conditions such as heat cramps, heat syncope, and heat exhaustion as well as the more severe condition known as heat stroke. [1] It can affect any or all anatomical systems. [2]
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It is one of the most common causes of disability among the elderly but can develop before the age of 65 when it is known as early-onset dementia or presenile dementia. [ 273 ] [ 274 ] Less than 1% of those with Alzheimer's have gene mutations that cause a much earlier development of the disease, around the age of 45, known as early-onset ...
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