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Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. It is frequently asymptomatic; if symptoms appear, they typically begin 3 to 14 days after infection.
Dengue fever: Dengue virus: primates mosquito bite (primarily by Aedes aegypti and Aedes albopictus) The earliest detailed descriptions of dengue-like illness appeared in medical records from 1779 to 1780, but has had a significant re-emergence in recent years (see for example 2019–20 dengue fever epidemic). Dirofilariasis: Dirofilaria spp.
The process of climate change has produced abundant rains and high temperatures, (a phenomenon called tropicalization) favouring the reproduction of the mosquito that transmits the dengue virus, advancing the epidemic this year by several weeks compared to previous seasons, which historically, Infection peaks tended to occur between March and April, suggesting a continued increase in cases. [11]
Epidemic dengue has become more common since the 1980s. By the late 1990s, dengue was the most important mosquito-borne disease affecting humans after malaria, with around 40 million cases of dengue fever and several hundred thousand cases of dengue hemorrhagic fever each year. Significant outbreaks of dengue fever tend to occur every five or ...
The dengue virus genome (genetic material) contains about 11,000 nucleotide bases, which code for the three different types of protein molecules (C, prM and E) that form the virus particle and seven other types of protein molecules (NS1, NS2a, NS2b, NS3, NS4a, NS4b, NS5) that are only found in infected host cells and are required for ...
Dengue is a Flaviviridae virus, with five genetic types. [8] [9] Here is the virus drawn as a 3-dimensional model of the envelope protein. [10]Dengue is in the same family as other well known viruses carried by mosquitoes that cause tropical diseases, such as yellow fever, West Nile, and Zika virus.
President Benigno Aquino III at the launching of the dengue vaccine school-based immunization program. In April 2016, the DOH launched the dengue vaccination campaign in Central Luzon, Calabarzon and Metro Manila, where about 700,000 individuals received at least one dose of the vaccine. [11] The government paid P3.5-billion for the vaccine. [10]