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The incidence of liver damage from herbal and dietary supplements is about 16–20% of all supplement products causing injury, with the occurrence growing globally over the early 21st century. [2] The most common liver injuries from weight loss and bodybuilding supplements involve hepatocellular damage and jaundice.
Androgens both regulate myostatin expression directly and upregulate follistatin expression. [3] YK-11, a selective androgen receptor modulator, is also a myostatin inhibitor. [4] [5] Resistance training reduces myostatin activity and increases follistatin activity. [6] Pharmacological myostatin inhibitors can therefore be considered exercise ...
Both medications have undergone testing and received approval by the U.S. Food & Drug Administration – Wegovy for targeting weight loss, and Ozempic for treating Type 2 diabetes.
A meta-study concluded that intake of protein supplements higher than around 1.6 g/kg/day do not further improve the gains in FFM (fat free mass) [3] “at least for younger individuals”, [3] with a confidence interval from 1.03 to 2.20 [3] so “it may be prudent to recommend ~2.2 g protein/kg/d for those seeking to maximize resistance ...
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A 2018 meta-review recommended that individuals may take up to 1.6 g/kg/day of protein with a confidence interval spanning from 1.03 to 2.20 so “it may be prudent to recommend ~2.2 g protein/kg/d for those seeking to maximise resistance training-induced gains in FFM.”. [20]
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The risk of using Ephedra gave rise to creatine. [6] Creatine is a supplement that was used by a lot of athletes in the 1992 Olympics where it gained most of its popularity from. Creatine was considered a form of pre-workout in the late 1990s until the early 2000s where it was then later used with a mixture of other supplements. [7]