Search results
Results from the WOW.Com Content Network
Francisco Juan Martínez Mojica [a] (born 5 October 1963) is a Spanish molecular biologist and microbiologist at the University of Alicante in Spain.He is known for his discovery of repetitive, functional DNA sequences in bacteria which he named CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).
CRISPR gene editing is a revolutionary technology that allows for precise, targeted modifications to the DNA of living organisms. Developed from a natural defense mechanism found in bacteria, CRISPR-Cas9 is the most commonly used system, that allows "cutting" of DNA at specific locations and either delete, modify, or insert genetic material.
Cas12a (CRISPR-associated protein 12a, previously known as Cpf1) is an RNA-guided endonuclease that forms an essential component of the CRISPR systems found in some bacteria and archaea. In its natural context, Cas12a targets and destroys the genetic material of viruses and other foreign mobile genetic elements , thereby protecting the host ...
8 July – Mitochondria are gene-edited for the first time, using a new kind of CRISPR-free base editor , by a team of researchers. [68] [69] 8 July: Researchers report that they succeeded in using a genetically altered variant of R. sulfidophilum to produce spidroins, the main proteins in spider silk. [70]
Since late 2002, Philippe's research activities have centered around CRISPR (clustered regularly interspaced short palindromic repeats). Early work was stimulated by with the aim of improving the durability of bacterial starter cultures to improve the manufacture of cheese and ice cream, [2] particularly efforts to address bacteriophages---viruses that infect bacteria.
In 2023, the company's Casgevy product for sickle cell disease became the first-ever CRISPR-based therapy approved by the Food and Drug Administration (FDA) as an important company milestone.
CRISPR interference (CRISPRi) is a genetic perturbation technique that allows for sequence-specific repression of gene expression in prokaryotic and eukaryotic cells. [1] It was first developed by Stanley Qi and colleagues in the laboratories of Wendell Lim , Adam Arkin, Jonathan Weissman , and Jennifer Doudna . [ 2 ]
Similar sandals found in Armenia are estimated to be 5,500 years old, while the shoes worn by “Ötzi the Iceman” — a prehistoric man found in Italy in 1991 — are dated to 5,300 years ago.