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A neoplasm (/ ˈ n iː oʊ p l æ z əm, ˈ n iː ə-/) [1] [2] is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia . The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger ...
236 Neoplasm of uncertain behavior of genitourinary organs; 237 Neoplasm of uncertain behavior of endocrine glands and nervous system. 237.0 Pituitary gland and craniopharyngeal duct. Pituitary adenoma; 237.7 Neurofibromatosis; 238 Neoplasm of uncertain behavior of other and unspecified sites and tissues 238.4 Polycythemia vera
Hematological malignancies are malignant neoplasms ("cancer"), and they are generally treated by specialists in hematology and/or oncology. In some centers "hematology/oncology" is a single subspecialty of internal medicine while in others they are considered separate divisions (there are also surgical and radiation oncologists).
A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often form a mass or lump, but may be distributed diffusely. [ 27 ] [ 28 ] All tumor cells show the six hallmarks of cancer .
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. GISTs arise in the smooth muscle pacemaker interstitial cell of Cajal, or similar cells. [2] They are defined as tumors whose behavior is driven by mutations in the KIT gene (85%), [2] PDGFRA gene (10%), [2] or BRAF kinase (rare).
Carcinoma in situ (CIS) is a group of abnormal cells. [1] [2] While they are a form of neoplasm, [3] there is disagreement over whether CIS should be classified as cancer.This controversy also depends on the exact CIS in question (e.g., cervical, skin, breast).
A subcategory of D48.1, Neoplasm of uncertain behavior of connective and other soft tissue, has been created with more specific codes: [50] D48.11: Desmoid tumor D48.110: Desmoid tumor of head and neck; D48.111: Desmoid tumor of chest wall; D48.112: Desmoid tumor, intrathoracic; D48.113: Desmoid tumor of abdominal wall
Cancer of unknown primary origin (CUP) is a cancer that is determined to be at the metastatic stage at the time of diagnosis, but a primary tumor cannot be identified. A diagnosis of CUP requires a clinical picture consistent with metastatic disease and one or more biopsy results inconsistent with a tumor cancer.