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Major factors influencing cardiac output – heart rate and stroke volume, both of which are variable. [1]In cardiac physiology, cardiac output (CO), also known as heart output and often denoted by the symbols , ˙, or ˙, [2] is the volumetric flow rate of the heart's pumping output: that is, the volume of blood being pumped by a single ventricle of the heart, per unit time (usually measured ...
Blood pressure. Aortic pressure; Ventricular pressure; Atrial pressure; Ventricular volume; Electrocardiogram; Arterial flow (optional) Heart sounds (optional) The Wiggers diagram clearly illustrates the coordinated variation of these values as the heart beats, assisting one in understanding the entire cardiac cycle. [1]
This allows the heart to cope with the required cardiac output at a relatively low right atrial pressure. We get what is known as a family of cardiac function curves, as the heart rate increases before the plateau is reached, and without the RAP having to rise dramatically to stretch the heart more and get the Starling effect. [citation needed]
A child aged 1–3 years old can have a heart rate of 80–130 bpm, a child aged 3–5 years old a heart rate of 80–120 bpm, an older child (age of 6–10) a heart rate of 70–110 bpm, and an adolescent (age 11–14) a heart rate of 60–105 bpm. [12] An adult (age 15+) can have a heart rate of 60–100 bpm. [12]
Venous blood with an oxygen concentration of 15 mL/100 mL would therefore lead to typical values of the a-vO 2 diff at rest of around 5 mL/100 mL. During intense exercise, however, the a-vO 2 diff can increase to as much as 16 mL/100 mL due to the working muscles extracting far more oxygen from the blood than they do at rest. [citation needed]
The theory of the velocity of the transmission of the pulse through the circulation dates back to 1808 with the work of Thomas Young. [9] The relationship between pulse wave velocity (PWV) and arterial wall stiffness can be derived from Newton's second law of motion (=) applied to a small fluid element, where the force on the element equals the product of density (the mass per unit volume ...
In "retrograde" flow, the flow would reverse (e.g. veins flow away from heart or arteries flow towards the heart). However, "retrograde" flow can be both abnormal or normal. For example, in portal hypertension, there is an abnormal portal venous flow where it flows away from the liver (hepatofugal flow) instead of the normal flow towards liver ...
The rate of blood flow out of the heart (often expressed in L/min) is known as the cardiac output (CO). Blood being pumped out of the heart first enters the aorta , the largest artery of the body. It then proceeds to divide into smaller and smaller arteries, then into arterioles , and eventually capillaries , where oxygen transfer occurs.