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2. Gabapentinoid - Wikipedia

   en.wikipedia.org/wiki/Gabapentinoid

   Gabapentin at a low dose of 100 mg has a T max (time to peak levels) of approximately 1.7 hours, while the T max increases to 3 to 4 hours at higher doses. [1] The T max of pregabalin is generally less than or equal to 1 hour at doses of 300 mg or less. [ 1 ]

3. Selegiline - Wikipedia

   en.wikipedia.org/wiki/Selegiline

   A small clinical randomized trial compared selegiline to methylphenidate, a first line treatment for ADHD, and reported equivalent efficacy as assessed by parent and teacher ratings. [239] In another small randomized controlled trial of selegiline for the treatment of adult ADHD, a high dose of the medication for 6 weeks was not significantly ...

4. Gabapentin - Wikipedia

   en.wikipedia.org/wiki/Gabapentin

   Gabapentin at a low dose of 100 mg has a T max (time to peak levels) of approximately 1.7 hours, while the T max increases to 3 to 4 hours at higher doses. [85] Food does not significantly affect the T max of gabapentin and increases the C max and area-under-curve levels of gabapentin by approximately 10%.

5. Pharmacology of selegiline - Wikipedia

   en.wikipedia.org/wiki/Pharmacology_of_selegiline

   [36] [37] For comparison, a single 0.5 mg dose by intravenous injection maximally inhibited platelet MAO-B activity by 80 ± 15% in the same study and this occurred within 5 minutes. [37] Using a logistic model , it was estimated that a 3.4 mg oral dose of selegiline would be equivalent to 0.5 mg intravenously (an 85% or 7:1 lower dose) in ...

6. GABA reuptake inhibitor - Wikipedia

   en.wikipedia.org/wiki/GABA_reuptake_inhibitor

   A GABA reuptake inhibitor (GRI) is a type of drug which acts as a reuptake inhibitor for the neurotransmitter gamma-Aminobutyric acid (GABA) by blocking the action of the gamma-Aminobutyric acid transporters (GATs). This in turn leads to increased extracellular concentrations of GABA and therefore an increase in GABAergic neurotransmission. [1]

7. Rasagiline - Wikipedia

   en.wikipedia.org/wiki/Rasagiline

   Rasagiline, sold under the brand name Azilect among others, is a medication which is used in the treatment of Parkinson's disease. [2] [6] It is used as a monotherapy to treat symptoms in early Parkinson's disease or as an adjunct therapy in more advanced cases. [7]

8. GABA receptor agonist - Wikipedia

   en.wikipedia.org/wiki/GABA_receptor_agonist

   Gamma-aminobutyric acid, a GABA-B receptor agonist. A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. [1] There are three receptors of the gamma-aminobutyric acid. The ...

9. Vigabatrin - Wikipedia

   en.wikipedia.org/wiki/Vigabatrin

   Vigabatrin reduced cholecystokinin tetrapeptide-induced symptoms of panic disorder, in addition to elevated cortisol and ACTH levels, in healthy volunteers. [12]Vigabatrin is also used to treat seizures in succinic semialdehyde dehydrogenase deficiency (SSADHD), which is an inborn GABA metabolism defect that causes intellectual disability, hypotonia, seizures, speech disturbance, and ataxia ...