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Persister cells are subpopulations of cells that resist treatment, and become antimicrobial tolerant by changing to a state of dormancy or quiescence. [1] [2] Persister cells in their dormancy do not divide. [3] The tolerance shown in persister cells differs from antimicrobial resistance in that the tolerance is not inherited and is reversible. [4]
Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. [1] Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, [2] and PARP inhibitors such as olaparib. [3]
It is a short-acting, thus will be degraded 2 hours after procedure, limiting the risk of ischemia to other healthy liver cells. [10] The most commonly used chemotherapy agents in TACE for HCC are (in decreasing order of frequency): doxorubicin, cisplatin, epirubicin, mitoxantrone, and mitomycin C. [11]
Natural transformation is a process of DNA transfer between cells, and is regarded as a form of bacterial sexual interaction. In the fruit fly Drosophila melanogaster , exposure to mitomycin C increases recombination during meiosis, a key stage of the sexual cycle. [ 5 ]
Donor lymphocyte infusion is the infusion in which lymphocytes from the original stem cell donor are infused, after the transplant, to augment an anti-tumor immune response or ensure that the donor stem cells remain engrafted. [1] [2] These donated white blood cells contain cells of the immune system that can recognize and destroy cancer cells.
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via ...
A Minnesota couple has reportedly been sentenced to four years after they locked their children in cages for "their safety." The couple was arrested and charged with 16 counts in June 2023. They ...
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.