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The inflammatory component is thought responsible for the symptoms of EPM; anti-inflammatory drugs that target the IL-6 pathway have been particularly effective at reversing symptoms. However, there is no vaccine to cure EPM. There are several ways that horse owners can potentially lessen the chances of their horse(s) getting EPM.
Neospora hughesi is an obligate protozoan apicomplexan parasite that causes myelitis and equine protozoal myeloencephalitis (EPM) in horses, and has only been documented in North America. [1] EPM is a neurological disease from lesions in the spinal cord , brain stem , or brain from parasites such as N. hughesi or Sarcocystis neurona . [ 2 ]
Early clinical signs of EPM include stumbling and frequent interference, which can often be mistaken for lameness of thoracic and/or pelvic limbs in horses. In horses, the disease often progresses gradually and includes clinical signs such as ataxia. In some horses mild clinical signs may herald a rapidly progressive disease course.
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The rodeo community is devastated after dozens of horses died at the Elk City, Oklahoma ranch. The company is still caring for 140 horses and calves. Oklahoma's Beutler and Son Rodeo Company loses ...
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Ponazuril (), sold by Merial, Inc., [1] now part of Boehringer Ingelheim, [2] under the trade name Marquis (15% w/w ponazuril), is a drug currently approved for the treatment of equine protozoal myeloencephalitis (EPM) in horses, caused by coccidia Sarcocystis neurona.