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Healthy individuals can be infected with the virus and show no signs or symptoms, due to the immune system's ability to keep the infection in check. Infection is of particular concern to the immunocompromised. Cancer patients receiving chemotherapy, AIDS patients, and organ transplant patients are all at a high risk of showing signs of infection.
Kaposi's sarcoma (KS) is a type of cancer that can form masses on the skin, in lymph nodes, in the mouth, or in other organs. [4] [6] The skin lesions are usually painless, purple and may be flat or raised. [6] [8] Lesions can occur singly, multiply in a limited area, or may be widespread. [6]
Herpes simplex, often known simply as herpes, is a viral infection caused by the herpes simplex virus. [5] Herpes infections are categorized by the area of the body that is infected. The two major types of herpes are oral herpes and genital herpes , though other forms also exist.
%shareLinks-quote="We really need to accelerate the development of vaccines against herpes simplex virus, and if a vaccine designed to prevent HSV-2 infection also prevented HSV-1, it would have ...
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Herpesviruses also cause cancer in animals, especially leukemias and lymphomas. [13] Human T cell lymphotropic virus was the first human retrovirus discovered by Robert Gallo and colleagues at NIH. [20] The virus causes Adult T-cell leukemia, a disease first described by Takatsuki and colleagues in Japan [21] and other neurological diseases ...
Fluid builup in the lower legs, feet and hands—also known as pedal edema— occurs because the heart’s ability to pump blood is too weak, which causes the blood to settle and accumulate in tissue.
In this fashion, the virus can persist in the cell (and thus the host) indefinitely. While primary infection is often accompanied by a self-limited period of clinical illness, long-term latency is symptom-free. [citation needed] Chromatin dynamics regulate the transcription competency of entire herpes virus genomes.