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Allodynia can also be caused when a nociceptor is damaged in the peripheral nerves. This can result in deafferentation, which means the development of different central processes from the surviving afferent nerve. With this situation, surviving dorsal root axons of the nociceptors can make contact with the spinal cord, thus changing the normal ...
Free nerve endings are unencapsulated and have no complex sensory structures. They are the most common type of nerve ending, and are most frequently found in the skin. They penetrate the dermis and end in the stratum granulosum. FNEs infiltrate the middle layers of the dermis and surround hair follicles.
A noxious stimulus is a stimulus strong enough to threaten the body's integrity (i.e. cause damage to tissue).Noxious stimulation induces peripheral afferents responsible for transducing pain (including A-delta and C-nerve fibers, as well as free nerve endings) throughout the nervous system of an organism.
Some nociceptors are unspecialized free nerve endings that have their cell bodies outside the spinal column in the dorsal-root ganglia. [3] Others are specialised structures in the skin such as nociceptive schwann cells. [4] Nociceptors are categorized according to the axons which travel from the receptors to the spinal cord or brain. After ...
Each muscle spindle consists of sensory nerve endings wrapped around special muscle fibers called intrafusal muscle fibers. Stretching an intrafusal fiber initiates a volley of impulses in the sensory neuron (a I-a neuron) attached to it. The impulses travel along the sensory axon to the spinal cord where they form several kinds of synapses:
The clitoris may be one of the least understood organs of the female anatomy. It may be pea-sized, but it packs a powerful punch thanks to thousands of nerve endings and an exclusive, unique ...
By comparison, the palm of one’s hand has 17,000 nerve endings — in a much, much larger area. Yet this study on the clitoris provides more than just a fun fact — it also can have major ...
Nerve terminals are the terminal part of the axon filled with neurotransmitters and are the location from which neurotransmitters are released. Nerve terminals may take different forms in different tissues. Nerve terminals appear like a button in the CNS, end plates in striated muscle and varicosities in many tissues including the gut. Buttons ...
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