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Methylsulfonylmethane is marketed as a dietary supplement with medical claims ranging from anti-inflammatory effects for pain management, skin condition and aging treatments, and immune system modulation. [9] [10] [11] No medical uses for MSM have been approved and there is limited evidence to support most of the claims.
Glucosamine is often sold in combination with other supplements such as chondroitin sulfate and methylsulfonylmethane. [citation needed] Glucosamine, along with commonly used chondroitin, is not routinely prescribed to treat people who have symptomatic osteoarthritis of the knee, as there is insufficient evidence that this treatment is helpful ...
Bergstrom Nutrition (originally named Cardinal Associates) was founded in 1988 by George Bergstrom and Bob Cowan, chemical engineers who worked with dimethylsulfoxide (DMSO) and dimethyl sulfone (DMSO2)/methylsulfonylmethane (MSM). The founders were first to introduce MSM as a dietary supplement to both the animal and human markets.
Please, someone review the Wiki article on the dietary supplement Methylsulfonylmethane (MSM). The current page content reads almost like stock sales material for a supplement vendor. Here is a key segment from the conclusion: "This remarkable nutrient has many valuable applications to human health.
The subset is designed to limit search results to citations from a broad spectrum of dietary supplement literature including vitamin, mineral, phytochemical, ergogenic, botanical, and herbal supplements in human nutrition and animal models. The subset will retrieve dietary supplement-related citations on topics including, but not limited to:
Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Methylsulfonylmethane. PubMed provides review articles from the past five years (limit to free review articles)
MMS methylates DNA predominantly on N7-deoxyguanosine and N3-deoxyadenosine, and to a much lesser extent also methylates at other oxygen and nitrogen atoms in DNA bases, and also methylates one of the non-carbon bound oxygen atoms of the phosphodiester linkage.
In the US, the popularity for vitamin E as a dietary supplement peaked around 2000, with popular doses of 400, 800 and 1000 IU/day. Declines in usage were attributed to publications of meta-analyses that showed either no benefits or negative consequences from vitamin E supplements.