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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution; although, only in a few cases are genes the primary cause of obesity. [4] [5]
Over 200 genes affect weight by determining activity level, food preferences, body type, and metabolism. [36] Having two copies of the allele called FTO increases the likelihood of both obesity and diabetes. [37] As such, obesity is a major feature of a number of rare genetic conditions that often present in childhood:
This allows a test of the genetic overlap between different phenotypes: for instance hair color and eye color. Environment and genetics may also interact, and heritability analyses can test for and examine these interactions (GxE models). A prerequisite for heritability analyses is that there is some population variation to account for.
Obesity has been observed throughout human history. Many early depictions of the human form in art and sculpture appear obese. [2] However, it was not until the 20th century that obesity became common — so much so that, in 1997, the World Health Organization (WHO) formally recognized obesity as a global epidemic [3] and estimated that the worldwide prevalence of obesity has nearly tripled ...
Gas chromatography–mass spectrometry-based technology with an integrated analytics system has now made it possible to test a newborn for over 100 mm genetic metabolic disorders. Because of the multiplicity of conditions, many different diagnostic tests are used for screening.
A healthy gut is about much more than proper digestion. Gut health boosts your immune system and contributes to heart and brain health. Gut health also plays a role in weight management.
Heredity, also called inheritance or biological inheritance, is the passing on of traits from parents to their offspring; either through asexual reproduction or sexual reproduction, the offspring cells or organisms acquire the genetic information of their parents.
A national study discovered that teens in the United States consumed significantly less alcohol and drugs in 2024 compared to past years. Teen alcohol use has steadily decreased from 2000 to 2024 ...