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  2. 2,4-Dinitrophenol - Wikipedia

    en.wikipedia.org/wiki/2,4-Dinitrophenol

    2,4-Dinitrophenol (2,4-DNP or simply DNP) is an organic compound with the formula HOC 6 H 3 (NO 2) 2. It has been used in explosives manufacturing and as a pesticide and herbicide. In humans, DNP causes dose-dependent mitochondrial uncoupling , causing the rapid loss of ATP as heat and leading to uncontrolled hyperthermia —up to 44 °C (111 ...

  3. Nicholas Bachynsky (criminal) - Wikipedia

    en.wikipedia.org/wiki/Nicholas_Bachynsky_(criminal)

    Nicholas Bachynsky (born 1942 or 1943) [1] is a Russian-born American former doctor and convicted fraudster. In the 1980s, he ran a weight loss clinic in Texas where he provided the unlicensed drug 2,4-Dinitrophenol (DNP) to patients under the name "Mitcal"; court filings reported that he had treated 14,000 people with the drug.

  4. HU6 - Wikipedia

    en.wikipedia.org/wiki/HU6

    HU6 is a prodrug of the mitochondrial uncoupler 2,4-dinitrophenol (DNP) that is intended to "minimize the rapid absorption and high peak blood concentrations of DNP to provide a wider therapeutic index and improve safety."

  5. What is the diet drug DNP and why is it so dangerous? - AOL

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  6. Ex-doctor sold ‘fat burner’ pills — containing a toxic ...

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  7. Anti-obesity medication - Wikipedia

    en.wikipedia.org/wiki/Anti-obesity_medication

    A prodrug of DNP, HU6, has been tested in clinical trials for weight loss and fatty liver disease. [ 22 ] Fibroblast growth factor-21 receptor agonists and drugs increasing FGF-21 activity are being investigated for obesity-related diseases; they can increase energy expenditure and several have been tested in humans.

  8. 4 of the Top Prescription Weight Loss Pills & How They Work - AOL

    www.aol.com/4-top-prescription-weight-loss...

    Top Prescription Weight Loss Pills. Anti-obesity medications (AOMs) date back to the 1940s — well before modern regulations from the FDA (U.S. Food and Drug Administration) (FDA) were in place ...

  9. Thermogenics - Wikipedia

    en.wikipedia.org/wiki/Thermogenics

    2,4-Dinitrophenol (DNP) is a very strong thermogenic drug used for fat loss which produces a dose-dependent increase in body temperature, to the point where it can induce death by hyperthermia. It works as a mitochondrial oxidative phosphorylation uncoupler, disrupting the mitochondrial electron transport chain .

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