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N-Phenylacetyl-l-prolylglycine ethyl ester is promoted as a nootropic and is a prodrug of cyclic glycine-proline. [a] [2] Other names include the brand name Noopept (Russian: Ноопепт), developmental code GVS-111, and proposed INN omberacetam. [2] [3] [4] Its synthesis was first reported in 1996. [2] It is orally available.
A little over 50% of all people with Down syndrome experience obstructive sleep apnea, [59] and some physicians advocate routine testing of this group. [60] In other craniofacial syndromes, the abnormal feature may actually improve the airway, but its correction may put the person at risk for obstructive sleep apnea after surgery when it is ...
[5] [15] In the 1960s, various further discoveries were made that led to the distinction between obstructive sleep apnea and sleep hypoventilation. [16] The term "Pickwickian syndrome" has fallen out of favor because it does not distinguish obesity hypoventilation syndrome and sleep apnea as separate disorders (which may coexist). [16] [17]
Two weeks later, they told me I had “high-moderate” sleep apnea and needed to acquire a continuous positive airway pressure, or CPAP, machine, at a cost of about $600.
McGinnis developed the "Nasal CPAP Mask System," a continuous positive airway pressure (CPAP) machine for the treatment of sleep apnea, [3] based on the original 1981 design by Dr. Colin Sullivan. [4] After receiving FDA approval in 1984, Respironics began selling the first commercially available CPAP machine a year later. [5]
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