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  2. Xanomeline/trospium chloride - Wikipedia

    en.wikipedia.org/wiki/Xanomeline/trospium_chloride

    Trospium chloride is a non-selective muscarinic antagonist. [1] The most common side effects of xanomeline/trospium chloride include nausea, indigestion, constipation, vomiting, hypertension, abdominal pain, diarrhea, tachycardia (increased heartbeat), dizziness, and gastroesophageal reflux disease. [2]

  3. Xanomeline - Wikipedia

    en.wikipedia.org/wiki/Xanomeline

    Xanomeline is an agonist that primarily targets the muscarinic acetylcholine receptor family of five muscarinic receptor subtypes, which are designated M 1-M 5. [2] While it binds with near identical affinity to all five of the muscarinic receptor subtypes as measured by displacement of a muscarinic radioligand, the preponderance of evidence suggests that xanomeline acts preferentially in the ...

  4. Muscarinic agonist - Wikipedia

    en.wikipedia.org/wiki/Muscarinic_agonist

    A muscarinic acetylcholine receptor agonist, also simply known as a muscarinic agonist or as a muscarinic agent, is an agent that activates the activity of the muscarinic acetylcholine receptor. [1] The muscarinic receptor has different subtypes, labelled M1-M5, allowing for further differentiation.

  5. Pilocarpine - Wikipedia

    en.wikipedia.org/wiki/Pilocarpine

    Other side effects include allergic reactions and retinal detachment. [1] Use is generally not recommended during pregnancy. [10] Pilocarpine is in the miotics family of medication. [11] It works by activating cholinergic receptors of the muscarinic type which cause the trabecular meshwork to open and the aqueous humor to drain from the eye. [1]

  6. Cevimeline - Wikipedia

    en.wikipedia.org/wiki/Cevimeline

    Cevimeline is a cholinergic agonist. [2] It has a particular effect on M 1 and M 3 receptors . [ 2 ] By activating the M 3 receptors of the parasympathetic nervous system , cevimeline stimulates secretion by the salivary glands , thereby alleviating dry mouth.

  7. Parasympathomimetic drug - Wikipedia

    en.wikipedia.org/wiki/Parasympathomimetic_drug

    A parasympathomimetic drug, sometimes called a cholinomimetic drug [1] or cholinergic receptor stimulating agent, [2] is a substance that stimulates the parasympathetic nervous system (PSNS). [ 3 ] [ 2 ] These chemicals are also called cholinergic drugs because acetylcholine (ACh) is the neurotransmitter used by the PSNS.

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  9. Cholinergic blocking drug - Wikipedia

    en.wikipedia.org/wiki/Cholinergic_blocking_drug

    Cholinergic blocking drugs are a group of drugs that block the action of acetylcholine (ACh), a neurotransmitter, in synapses of the cholinergic nervous system. [1] They block acetylcholine from binding to cholinergic receptors, namely the nicotinic and muscarinic receptors.

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