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Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. [2] It is used to treat vaginal yeast infections , oral thrush , diaper rash , tinea versicolor , and types of ringworm including athlete's foot and jock itch . [ 2 ]
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Clotrimazole Clotrimazole is widely used to treat fungal infections on different parts of the body, including infections in the otitis externa (ear), the skin, regions of the vagina, and vulva. It is available in the form of pessaries, liquid, creams, and spray.
A medical professional administering nose drops Instillation of eye drops. A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. [1]
Its antifungal activity has been demonstrated in in vivo and in vitro studies to be comparable to that of clotrimazole and higher than bifonazole. [1] Mechanism of action
Econazole is used as a cream to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch.It is also sold in Canada under the brand name Ecostatin as vaginal ovules to treat vaginal thrush.
Zinc pyrithione concentration of up to 2% is allowed for products when they are formulated to be applied and then washed off after brief exposure. Alternatively, up to 0.25 percent when formulated to be left on the skin or scalp [ 20 ]
Ketoconazole is a racemic mixture consisting of cis-(2S,4R)-(−) and cis-(2R,4S)-(+) enantiomers. [10] The cis -(2 S ,4 R ) isomer was more potent in inhibiting progesterone 17α,20-lyase than its enantiomer ( IC 50 values of 0.05 and 2.38 μ M, respectively) and in inhibiting 11β-hydroxylase (IC 50 values of 0.152 and 0.608 μ M, respectively).
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