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  2. Neutral theory of molecular evolution - Wikipedia

    en.wikipedia.org/wiki/Neutral_theory_of...

    A coherent theory of neutral evolution was first proposed by Motoo Kimura in 1968 [9] and by King and Jukes independently in 1969. [10] Kimura initially focused on differences among species; King and Jukes focused on differences within species. Many molecular biologists and population geneticists also contributed to the development of the ...

  3. The Neutral Theory of Molecular Evolution - Wikipedia

    en.wikipedia.org/wiki/The_Neutral_Theory_of...

    The Neutral Theory of Molecular Evolution is an influential monograph written in 1983 by Japanese evolutionary biologist Motoo Kimura.While the neutral theory of molecular evolution existed since his article in 1968, [1] Kimura felt the need to write a monograph with up-to-date information and evidences showing the importance of his theory in evolution.

  4. Alternatives to Darwinian evolution - Wikipedia

    en.wikipedia.org/wiki/Alternatives_to_Darwinian...

    The neutral theory of molecular evolution, proposed by Motoo Kimura in 1968, holds that at the molecular level most evolutionary changes and most of the variation within and between species is not caused by natural selection but by genetic drift of mutant alleles that are neutral.

  5. HKA test - Wikipedia

    en.wikipedia.org/wiki/HKA_test

    Neutral Evolution Theory, first proposed by Kimura in a 1968 paper, and later fully defined and published in 1983, is the basis for many statistical tests that detect selection at the molecular level. Kimura noted that there was much too high of a rate of mutation within the genome (i.e. high polymorphism) to be strictly under directional ...

  6. Outline of evolution - Wikipedia

    en.wikipedia.org/wiki/Outline_of_evolution

    Neutral theoryTheory of evolution by changes at the molecular level; Shifting balance theory – One version of the theory of evolution; Price equation – Description of how a trait or gene changes in frequency over time; Coefficient of relationship – Mathematical guess about inbreeding; Fitness – Expected reproductive success

  7. Neutral mutation - Wikipedia

    en.wikipedia.org/wiki/Neutral_mutation

    Neutral mutation has become a part of the neutral theory of molecular evolution, proposed in the 1960s. This theory suggests that neutral mutations are responsible for a large portion of DNA sequence changes in a species. For example, bovine and human insulin, while differing in amino acid sequence are still able to perform the same function ...

  8. Non-Darwinian Evolution (paper) - Wikipedia

    en.wikipedia.org/wiki/Non-Darwinian_Evolution...

    Non-Darwinian Evolution" is a scientific paper written by Jack Lester King and Thomas H. Jukes and published in 1969. It is credited, along with Motoo Kimura's 1968 paper "Evolutionary Rate at the Molecular Level", with proposing what became known as the neutral theory of molecular evolution.

  9. Genetic hitchhiking - Wikipedia

    en.wikipedia.org/wiki/Genetic_hitchhiking

    The neutral theory of molecular evolution assumes that most new mutations are either deleterious (and quickly purged by selection) or else neutral, with very few being adaptive. It also assumes that the behavior of neutral allele frequencies can be described by the mathematics of genetic drift.

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