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A coherent theory of neutral evolution was first proposed by Motoo Kimura in 1968 [9] and by King and Jukes independently in 1969. [10] Kimura initially focused on differences among species; King and Jukes focused on differences within species. Many molecular biologists and population geneticists also contributed to the development of the ...
The Neutral Theory of Molecular Evolution is an influential monograph written in 1983 by Japanese evolutionary biologist Motoo Kimura.While the neutral theory of molecular evolution existed since his article in 1968, [1] Kimura felt the need to write a monograph with up-to-date information and evidences showing the importance of his theory in evolution.
These ideas developed into mutationism, the mutation theory of evolution. [ 29 ] [ 30 ] This held that species went through periods of rapid mutation, possibly as a result of environmental stress, that could produce multiple mutations, and in some cases completely new species, in a single generation, based on de Vries's experiments with the ...
Neutral mutation has become a part of the neutral theory of molecular evolution, proposed in the 1960s. This theory suggests that neutral mutations are responsible for a large portion of DNA sequence changes in a species. For example, bovine and human insulin, while differing in amino acid sequence are still able to perform the same function ...
Neutral theory – Theory of evolution by changes at the molecular level; Shifting balance theory – One version of the theory of evolution; Price equation – Description of how a trait or gene changes in frequency over time; Coefficient of relationship – Mathematical guess about inbreeding; Fitness – Expected reproductive success
Non-Darwinian Evolution" is a scientific paper written by Jack Lester King and Thomas H. Jukes and published in 1969. It is credited, along with Motoo Kimura's 1968 paper "Evolutionary Rate at the Molecular Level", with proposing what became known as the neutral theory of molecular evolution.
The modern synthesis [a] was the early 20th-century synthesis of Charles Darwin's theory of evolution and Gregor Mendel's ideas on heredity into a joint mathematical framework. Julian Huxley coined the term in his 1942 book, Evolution: The Modern Synthesis .
Neutral evolution can therefore be visualised as a population diffusing from one set of sequence nodes, through the neutral network, to another cluster of sequence nodes. Since the majority of evolution is thought to be neutral, [ 14 ] [ 15 ] a large proportion of gene change is the movement though expansive neutral networks.